RADIL Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16899804	Proteintech 20284-1-AP-20UL	20 μL
16889804	Proteintech 20284-1-AP-150UL	150 μL

Description

Radil is a broadly expressed adapter protein that contains a RA-like domain, a PDZ domain and a DIL domain. Like RAPL and RIAM, Radil interacts preferentially with active GTP-bound Rap1, and overexpression of Radil enhances integrin-mediated adhesion. In addition, Radil knock down inhibits cell-substrate adhesion in HT1080, AD293, and NMuMG cells and results in migration defects in SW1353 and zebrafish neural crest cells. Radil regulates neutrophil adhesion by specifically enhancing beta2-integrin activation, as well as focal adhesion kinase (FAK) and paxillin phosphorylation.

Specifications

• Antigen: RADIL
• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q96JH8
• Gene ID (Entrez): 55698
• Immunogen: RADIL Fusion Protein Ag13996
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: RADIL

• Concentration: 0.43 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: KIAA1849, RADIL
• Gene Symbols: RADIL
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody