Invitrogen™ RAD54L2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550258

Product Code. 15694185

Description

The antibody detects endogenous levels of total RAD54L2 protein.

Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.

Specifications

• Antigen: RAD54L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD54L2
• Gene Alias: Androgen receptor-interacting protein 4; AR interacting protein 4; ARIP4; Helicase ARIP4; HSPC325; KIAA0809; Rad54 like 2; RAD54L2; RAD54-like 2 (S. cerevisiae); RAD54-like protein 2; RGD1561889; SRISNF2L
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23132
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 2.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9Y4B4
• Gene Symbols: RAD54L2
• Immunogen: Fusion protein corresponding to residues near the C terminal of human RAD54-like 2 (S. cerevisiae).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG