Invitrogen™ RAD51C Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588579

Product Code. 16536781

Description

Immunogen sequence: MRGKTFRFEM QRDLVSFPLS PAVRVKLVSA GFQTAEELLE VKPSELSKEV GISKAEALET LQIIRRECLT NKPRYAGTSE SHKKCTALEL LEQEHTQGFI ITFCSALDDI LGGGVPLMKT TEICGAPGVG KTQLW.

ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.

Specifications

• Antigen: RAD51C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD51C
• Gene Alias: BROVCA3; DNA repair protein RAD51 homolog 3; FANCO; MGC104277; R51H3; RAD51 homolog C; RAD51 paralog C; RAD51C; RAD51L2; RAD51-like protein 2; RGD1563765; yeast RAD51 homolog 3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5889
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunocytochemistry
• Concentration: 0.23 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43502
• Gene Symbols: RAD51C
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C (NP_0028671).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG