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Invitrogen™ RAC3 Recombinant Rabbit Monoclonal Antibody (K01_1X48)
Description
Immunogen sequence: DKDTIERLRD KKLA.
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Specifications
Specifications
| Antigen | RAC3 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_1X48 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4 |
| Gene | RAC3 |
| Gene Accession No. | P60763, P60764 |
| Gene Alias | OTTMUSP00000004488; p21 Rac3; p21-Rac3; Rac1B; RAC3; RAC3_HUMAN; RAS related C3 botulinum substrate 3; Ras related C3 botulinum toxin substrate 3; Ras-related C3 botulinum toxin substrate 3; Rho family small GTP binding protein Rac3; RP23-84C12.18 |
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