TBX1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of TBX1.

Brand:  Abnova PAB17338.100ug

Product Code. 16072767

Description

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq

Specifications

• Antigen: TBX1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of TBX1.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene Alias: CAFS/CTHM/DGCR/DGS/DORV/TBX1C/TGA/VCFS
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of total TBX1 protein.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunofluorescence (1:500-1:1000) ELISA (1:20000) The optimal working dilution should be determined by the end user.
• Gene: TBX1
• Gene Symbols: TBX1
• Immunogen: A synthetic peptide corresponding to C-terminus of human TBX1.
• Regulatory Status: RUO
• Gene ID (Entrez): 6899
• Target Species: Human
• Form: Liquid

For Research Use Only