PARP1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PARP1.

Brand:  Abnova PAB4469.400uL

Product Code. 16079067

Description

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq

Specifications

• Antigen: PARP1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PARP1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: ADPRT/ADPRT1/PARP/PARP-1/PPOL/pADPRT-1
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 142
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: PARP1
• Gene Symbols: PARP1
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PARP1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only