PAK4 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PAK4.

Brand:  Abnova PAB18879.100ug

Product Code. 16003497

Description

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: PAK4
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PAK4.
• Formulation: In buffer containing 0.02% sodium azide
• Gene Symbols: PAK4
• Immunogen: A synthetic peptide corresponding to 14 amino acids at N-terminus of human PAK4.
• Regulatory Status: RUO
• Gene ID (Entrez): 10298
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000-1:40000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Gene: PAK4
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only