PAK3, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PAK3.

Brand:  Abnova PAB2300.400uL

Product Code. 16094397

Description

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of nonsyndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq

Specifications

• Antigen: PAK3
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PAK3.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: CDKN1A/MRX30/MRX47/OPHN3/PAK3beta/bPAK/hPAK3
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5063
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: PAK3
• Gene Symbols: PAK3
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human PAK3.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only