NRG1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of NRG1.

Brand:  Abnova PAB28170.50ug

Product Code. 16087897

Description

The protein encoded by this gene was originally identified as a 44kDa glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq

Specifications

• Antigen: NRG1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NRG1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: ARIA/GGF/GGF2/HGL/HRG/HRG1/HRGA/NDF/SMDF
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3084
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/ml)
• Gene: NRG1
• Gene Symbols: NRG1
• Immunogen: A synthetic peptide corresponding to 15 amino acids at N-terminus region of human NRG1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only