NLRP8, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody rasied against synthetic peptide of NLRP8.

Brand:  Abnova PAB19306.100ug

Product Code. 16053857

Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP8, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM

Specifications

• Antigen: NLRP8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: NLRP8
• Gene Symbols: NLRP8
• Immunogen: A synthetic peptide corresponding to 16 amino acids near N-terminus of human NLRP8.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody rasied against synthetic peptide of NLRP8.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: CLR19.2/NALP8/NOD16/PAN4
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 126205
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only