MYC Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MYC.

Brand:  Abnova PAB1902.400uL

Product Code. 16013617

Description

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]

Specifications

• Antigen: MYC
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MYC.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: bHLHe39/c-Myc
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 4609
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: MYC
• Gene Symbols: MYC
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S373 of human MYC.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only