MMP8 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MMP8.

Brand:  Abnova PAB12713.100ug

Product Code. 16040087

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq

Specifications

• Antigen: MMP8
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MMP8.
• Formulation: In TBS, pH 7.2 (BSA, 10% Proclin300)
• Gene Alias: CLG1/HNC/PMNL-CL
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes ∼65 KDa of MMP8.
• Content And Storage: Store at 4°C. For long term storage store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. Upon initial thawing apportion into working aliquots and store at -80°C for up to six months.

• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: MMP8
• Gene Symbols: MMP8
• Immunogen: A synthetic peptide corresponding to the hinge region of human MMP8.
• Regulatory Status: RUO
• Gene ID (Entrez): 4317
• Target Species: Human
• Form: Liquid

For Research Use Only