MLH3 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MLH3.

Brand:  Abnova PAB17549.100ug

Product Code. 16162330

Description

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq

Specifications

• Antigen: MLH3
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MLH3.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene Alias: HNPCC7/MGC138372
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of total MLH3 protein.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user.
• Gene: MLH3
• Gene Symbols: MLH3
• Immunogen: A synthetic peptide corresponding to internal of human MLH3.
• Regulatory Status: RUO
• Gene ID (Entrez): 27030
• Target Species: Human
• Form: Liquid

For Research Use Only