ITGB2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ITGB2.

Brand:  Abnova PAB12294.100ug

Product Code. 16203270

Description

The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq

Specifications

• Antigen: ITGB2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ITGB2.
• Formulation: Lyophilized from 0.9mg NaCl, 0.2mg Na₂HPO₄ (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
• Gene Alias: CD18/LAD/LCAMB/LFA-1/MAC-1/MF17/MFI7
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 3689
• Target Species: Human
• Form: Lyophilized

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ITGB2
• Gene Symbols: ITGB2
• Immunogen: A synthetic peptide corresponding to N-terminus of human ITGB2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: The synthetic peptide of this antibody different from the related mouse sequence by five amino acids.
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

For Research Use Only