IL10RA Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of IL10RA.

Brand:  Abnova PAB18395.100ug

Product Code. 16102910

Description

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq

Specifications

• Antigen: IL10RA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunofluorescence (1:500-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Gene: IL10RA
• Gene Symbols: IL10RA
• Immunogen: A synthetic peptide corresponding to residues surrounding Y496 of human IL10RA.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to IL10RA.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunofluorescence, Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of IL10RA.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: CDW210A/HIL-10R/IL-10R1/IL10R
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 3587
• Target Species: Human
• Form: Liquid

For Research Use Only