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HIRA Rabbit anti-Human, Polyclonal Antibody, Abnova™
Description
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq
Specifications
Specifications
| Antigen | HIRA |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of HIRA. |
| Dilution | ELISA (1:1000) Western Blot (1:50-100) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | HIRA |
| Gene Alias | DGCR1/TUP1/TUPLE1 |
| Gene Symbols | HIRA |
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For Research Use Only
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