HDAC1 (phospho S421/S423), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of HDAC1.

Brand:  Abnova PAB16973.100ug

Product Code. 16062517

Description

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq

Specifications

• Antigen: HDAC1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of HDAC1.
• Formulation: In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
• Gene Alias: DKFZp686H12203/GON-10/HD1/RPD3/RPD3L1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.
• Gene: HDAC1
• Gene Symbols: HDAC1
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S421/S423 of human HDAC1.
• Regulatory Status: RUO
• Gene ID (Entrez): 3065
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only