GLI2, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GLI2.

Brand:  Abnova PAB10051.100ug

Product Code. 16019026

Description

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq

Specifications

• Antigen: GLI2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GLI2.
• Formulation: In 20mM KH₂PO₄, 150mM NaCl, pH 7.2 (0.01% sodium azide)
• Gene Accession No.: P10070;NP_084655(isoformalpha)
• Gene Symbols: GLI2
• Immunogen: A synthetic peptide corresponding to amino acids 46-60 of human GLI2.
• Regulatory Status: RUO
• Gene ID (Entrez): 2736
• Target Species: Bovine, Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:10,000-1:3,0000) Western Blot (1:500-1:2000) Immunohistochemistry (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Gene: GLI2
• Gene Alias: HPE9/THP1/THP2
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Expect reactivity with all isoforms of this protein.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only