GLE1, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GLE1.

Brand:  Abnova PAB16679.100ug

Product Code. 16062277

Description

This gene encodes a predicted 75kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: GLE1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GLE1.
• Formulation: In PBS (0.02% sodium azide)
• Gene Accession No.: NP_001003722
• Gene Symbols: GLE1
• Immunogen: A synthetic peptide corresponding to C-terminus 15 amino acids of human GLE1.
• Regulatory Status: RUO
• Gene ID (Entrez): 2733
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: GLE1
• Gene Alias: GLE1L/LCCS/LCCS1/hGLE1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only