FGF8, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of FGF8.

Brand:  Abnova PAB12306.100ug

Product Code. 16253270

Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq

Specifications

• Antigen: FGF8
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of FGF8.
• Formulation: Lyophilized from 0.9mg NaCl, 0.2mg Na₂HPO₄ (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
• Gene Alias: AIGF/HBGF-8/MGC149376
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2253
• Target Species: Human, Mouse, Rat
• Form: Lyophilized

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: FGF8
• Gene Symbols: FGF8
• Immunogen: A synthetic peptide corresponding to amino acids at C-terminus of human FGF8.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Identical to the related rat and mouse sequence.
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

For Research Use Only