ESR1 (phospho S167), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ESR1.

Brand:  Abnova PAB12621.100ug

Product Code. 16099986

Description

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq]

Sequence: LASTN

Specifications

• Antigen: ESR1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ESR1.
• Formulation: In TBS, pH 7.2 (BSA, 10% Proclin300)
• Gene Alias: DKFZp686N23123/ER/ESR/ESRA/Era/NR3A1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes ∼67 KDa of human ESR1 at the phosphorylation site of SESR1 167. It does not cross react to non-phosphorylated peptide.
• Content And Storage: Store at 4°C. For long term storage store at -20°C or lower.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (1:200) The optimal working dilution should be determined by the end user.
• Gene: ESR1
• Gene Symbols: ESR1
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S167 of human ESR1.
• Regulatory Status: RUO
• Gene ID (Entrez): 2099
• Target Species: Human
• Form: Liquid

For Research Use Only