DPEP1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of DPEP1.

Brand:  Abnova PAB26064.50ug

Product Code. 16096247

Description

DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990 [PubMed 2303490]).[supplied by OMIM

Specifications

• Antigen: DPEP1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of DPEP1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: P16444
• Gene Symbols: DPEP1
• Immunogen: A synthetic peptide corresponding to 18 amino acids at N-terminus of human DPEP1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: DPEP1
• Gene Alias: MBD1/MDP/RDP
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1800
• Target Species: Human
• Form: Liquid

For Research Use Only