COPS5 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of COPS5.

Brand:  Abnova PAB26896.100uL

Product Code. 16097067

Description

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq

Specifications

• Antigen: COPS5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Gene: COPS5
• Gene Alias: CSN5/JAB1/MGC3149/MOV-34/SGN5
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 10987
• Target Species: Human, Mouse
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of COPS5.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene Accession No.: Q92905
• Gene Symbols: COPS5
• Immunogen: A synthetic peptide corresponding to human COPS5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: COPS5 polyclonal antibody detects endogenous levels of COPS5 protein.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only