CDH1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CDH1.

Brand:  Abnova PAB7893.100uL

Product Code. 16090708

Description

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq

Specifications

• Antigen: CDH1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CDH1.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
• Gene Accession No.: P12830
• Gene Symbols: CDH1
• Immunogen: A synthetic peptide corresponding to C-terminus of human CDH1.
• Regulatory Status: RUO
• Gene ID (Entrez): 999
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user.
• Gene: CDH1
• Gene Alias: Arc-1/CD324/CDHE/ECAD/LCAM/UVO
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This sequence is conserved in rat and mouse E-cadherin, and has low homology to other cadherin family members.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only