CDC27 Rabbit anti-Chicken, Chimpanzee, Dog, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CDC27.

Brand:  Abnova PAB9986.100ug

Product Code. 16092018

Description

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CDC27
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CDC27.
• Formulation: In 20mM KH₂PO₄, 150mM NaCl, pH 7.2 (0.01% sodium azide)
• Gene Accession No.: P30260;NP_001247
• Gene Symbols: CDC27
• Immunogen: A synthetic peptide corresponding to amino acids 422-430 of human CDC27.
• Regulatory Status: RUO
• Gene ID (Entrez): 996
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:5000-1:40000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Gene: CDC27
• Gene Alias: APC3/CDC27Hs/D0S1430E/D17S978E/HNUC
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Canine, Chicken, Chimpanzee, Human, Mouse, Rat
• Form: Liquid

For Research Use Only