CBL Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against a synthetic peptide of CBL.

Brand:  Abnova PAB0864.200ug

Product Code. 16088946

Description

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq

Specifications

• Antigen: CBL
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against a synthetic peptide of CBL.
• Formulation: In PBS (0.2% gelatin, 0.09% sodium azide)
• Gene Alias: C-CBL/CBL2/RNF55
• Host Species: Rabbit
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:200) The optimal working dilution should be determined by the end user.
• Gene: CBL
• Gene Symbols: CBL
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CBL.
• Regulatory Status: RUO
• Gene ID (Entrez): 867
• Content And Storage: Store at 4°C. Do not freeze.

For Research Use Only