CASP2 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CASP2.

Brand:  Abnova PAB12286.100ug

Product Code. 16273260

Description

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq

Specifications

• Antigen: CASP2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CASP2.
• Formulation: Lyophilized from 0.9mg NaCl, 0.2mg Na₂HPO₄ (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
• Gene Accession No.: BC002427
• Gene Symbols: CASP2
• Immunogen: A synthetic peptide corresponding to amino acids at C-terminus of human CASP2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Identical to the related rat sequence.
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CASP2
• Gene Alias: CASP-2/ICH-1L/ICH-1L/1S/ICH1/NEDD2
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 835
• Target Species: Human, Mouse, Rat
• Form: Lyophilized

For Research Use Only