CARD14, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of CARD14.

Brand:  Abnova PAB27180.100ug

Product Code. 16057367

Description

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq

Specifications

• Antigen: CARD14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CARD14
• Gene Alias: BIMP2/CARMA2
• Host Species: Rabbit
• Purification Method: Peptide affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 79092
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of CARD14.
• Formulation: In PBS (0.02% sodium azide)
• Gene Accession No.: NP_007715
• Gene Symbols: CARD14
• Immunogen: A synthetic peptide corresponding to 14 amino acids at C-terminus of human CARD14.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: CARD14 antibody is human specific. At least three isoforms of CARD14 are known to exist; this antibody will only detect isoform 1. CARD14 antibody is predicted not to cross-react with other CARMA proteins.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

For Research Use Only