BMPR1A Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BMPR1A.

Brand:  Abnova PAB3833.400uL

Product Code. 16068807

Description

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55kDa and type II receptors of about 70-80kDa. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq

Specifications

• Antigen: BMPR1A
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BMPR1A.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: BMRA_HUMAN
• Gene Symbols: BMPR1A
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 29-58 at N-terminus of human BMPR1A.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunofluorescence, Western Blot, Western Blot
• Conjugate: Unconjugated
• Dilution: Immunofluorescence (1:10-50) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: BMPR1A
• Gene Alias: 10q23del/ACVRLK3/ALK3/CD292
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 657
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only