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BAX Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16152320
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Quantity:
100 μg
Unit Size:
100µg
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16152320 100 μg 100µg
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Product Code. 16152320 Supplier Abnova Supplier No. PAB17538.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of BAX.

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq

Specifications

Antigen BAX
Applications ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of BAX.
Dilution Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Gene BAX
Gene Accession No. P55269
Gene Alias BCL2L4
Gene Symbols BAX
Host Species Rabbit
Immunogen A synthetic peptide corresponding to internal of human BAX.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 581
Test Specificity This antibody detects endogenous levels of total BAX protein (cytoplasmic isoform delta).
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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