BAIAP2, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of BAIAP2.

Brand:  Abnova PAB4062.400uL

Product Code. 16078907

Description

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms

Specifications

• Antigen: BAIAP2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of BAIAP2.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_006331
• Gene Symbols: BAIAP2
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human BAIAP2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Gene: BAIAP2
• Gene Alias: BAP2/IRSP53
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 10458
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only