APP Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of APP.

Brand:  Abnova PAB9763.100ug

Product Code. 16061888

Description

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: APP
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of APP.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: AAA/ABETA/ABPP/AD1/APPI/CTFgamma/CVAP/PN2
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: APP
• Gene Symbols: APP
• Immunogen: A synthetic peptide corresponding to amino acids 653-662 of human APP.
• Regulatory Status: RUO
• Gene ID (Entrez): 351
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only