APEX2, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of APEX2.

Brand:  Abnova PAB0203.200uL

Product Code. 16098606

Description

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). [provided by RefSeq]

Specifications

• Antigen: APEX2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of APEX2.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: APE2/APEXL2/XTH2
• Host Species: Rabbit
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: APEX2
• Gene Symbols: APEX2
• Immunogen: A synthetic peptide corresponding to human APEXL2.
• Regulatory Status: RUO
• Gene ID (Entrez): 27301
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only