Invitrogen™ RAB5C Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110681

Product Code. 17168603

Description

Immunogen sequence: NSLLFMETSA KTAMNVNEIF MAIAKKLPKN EPQNATGAPG RNRGVDLQEN NPASRSQCCS N Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 95%.

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles.

Specifications

• Antigen: RAB5C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB5C
• Gene Alias: AI326010; L1880; RAB; RAB5B; RAB5B, member RAS oncogene family; RAB5C; Rab5c protein; RAB5C, member of RAS oncogene family; RAB5C, member RAS oncogene family; RAB5C, member RAS oncogene family isoform b; RAB5CL; RAB5L; RABL; Ras-related protein Rab-5C; small GTPase; wu:fb98b08; wu:fi16g01
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5878
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P51148
• Gene Symbols: RAB5C
• Immunogen: Recombinant protein fragment of Human RAB5C (Product #RP-102038)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG