Invitrogen™ RAB5 Recombinant Rabbit Monoclonal Antibody (24GB4520)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30275132	Invitrogen™ MA557662	100 μL
30275596	Invitrogen™ MA557663	20 μL

Description

RAB5 Recombinant Monoclonal Antibody for Western Blot, Flow

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.

Specifications

• Antigen: RAB5
• Concentration: 0.7 mg/mL
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: M0RC99, P20339, Q9CQD1
• Gene ID (Entrez): 271457, 5868, 64633
• Immunogen: A synthesized peptide derived from human Rab5 (aa 3-19).
• Product Type: Antibody

• Clone: 24GB4520
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: RAB5A
• Gene Alias: 2410015H04Rik; AI663973; AU021172; nnyRab5a; Rab 5; Rab 5A; RAB5; RAB5A; RAB5A, member RAS oncogene family; Ras related protein; RAS-associated protein RAB5A; ras-related protein Rab-5A; Small GTP-binding protein rab5
• Gene Symbols: RAB5A
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography