Invitrogen™ RAB1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5104067

Product Code. 16680515

Description

Antibody detects endogenous levels of total RAB1B.

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.

Specifications

• Antigen: RAB1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB1B
• Gene Alias: 1110011F09Rik; RAB1B; RAB1B, member RAS oncogene family; Rab1bl; RAB1B-like, member RAS oncogene family; ras-related protein Rab-1B; small GTP-binding protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100126191, 76308, 81876
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P10536, Q9D1G1, Q9H0U4
• Gene Symbols: RAB1B
• Immunogen: A synthesized peptide derived from human RAB1B(Accession Q9H0U4), corresponding to amino acid residues T72-K122.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG