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  6. (R)-(-)-Gossypol acetic acid, MedChemExpress

(R)-(-)-Gossypol acetic acid, MedChemExpress

Product Code. 16452637
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Quantity:
10 mg
50 mg
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10mg
50mg
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Product Code. 16452637

Brand: Medchem Express HY15464A

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Description

MedChemExpress (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.

Specifications

Chemical Name or Material (R)-(-)-Gossypol acetic acid
Physical Form Solid
CAS 866541-93-7
Color Dark Brown
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C32H34O10
For Use With (Application) Cancer-programmed cell death
Synonym AT-101 (acetic acid) (-)-Gossypol acetic acid (R)-Gossypol acetic acid
Solubility Information DMSO : 25 mg/mL (43.21 mM; Need ultrasonic)
SMILES OC1=C2C(C=O)=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@]1[C@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=C(C=O)C4=C3O.CC(O)=O.[R]
Molecular Weight (g/mol) 578.61
Formula Weight 578.61
Percent Purity 96.98%
Grade Research
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Research purposes only

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