R&D Systems™ Recombinant Human IL-12 Protein

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Product Code	Brand	Formulation	Quantity
18325007	R&D Systems™ 219-IL-005/CF	Lyophilized from a 0.2μm filtered solution in PBS.	5μg
18358947	R&D Systems™ 219-IL-005	Lyophilized from a 0.2μm filtered solution in PBS with BSA as a carrier protein.	5μg
18166780	R&D Systems™ 219-IL-025	Lyophilized from a 0.2μm filtered solution in PBS with BSA as a carrier protein.	25μg
18106650	R&D Systems™ 219-IL-025/CF	Lyophilized from a 0.2μm filtered solution in PBS.	25μg

Description

Measured in a cell proliferation assay using PHA-stimulated human T lymphoblasts. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The ED50 for this effect is 0.01-0.05 ng/mL.

Specifications

• Gene ID (Entrez): 3592
• Name: IL-12
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Conjugate: Unconjugated
• Purity or Quality Grade: 97%, by SDS-PAGE with silver staining.

• Molecular Weight (g/mol): 34.7 kDa (p40) & 22.5 kDa (p35)
• Source: Spodoptera frugiperda,Sf 21 (baculovirus)-derived human IL-12 protein, (N-terminus) Human IL-12 p40 (Ile23-Ser328) Accession &Num; P29460 Human IL-12 p35 (Arg23-Ser219) Accession &Num; P29459 (C-terminus)
• Structural Form: Disulfide-linked heterodimer
• Recombinant: Recombinant