missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ ABT 089 Dihydrochloride

Tocris Bioscience™ ABT 089 Dihydrochloride
GREENER_CHOICE

Product Code. 18766258
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18766258

Brand: Tocris Bioscience™ 5079/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

High affinity and selective α4β2 nAChR partial agonist

ABT 089 dihydrochloride is a high affinity and selective α4β2 partial agonist (Ki = 16 nM). Exhibits >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors respectively. Neuroprotective against glutamate-induced toxicity in rat cortical neurons in vitro. Enhances cognitive performance in vivo. Orally bioavailable and brain penetrant.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material ABT 089 dihydrochloride
CAS 161416-61-1
Synonym 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride
Quantity 10 mg
Solubility Soluble to 100mM in water and to 20mM in DMSO
Molecular Formula C11H16N2O·2HCl
Formula Weight 265.18
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.