(R)-1-Boc-3-hydroxypiperidine, 97%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
15469297	Thermo Scientific Alfa Aesar H52556.03	1 g
15479297	Thermo Scientific Alfa Aesar H52556.06	5 g

Description

(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Chemical Identifiers

• CAS: 143900-43-0
• Molecular Weight (g/mol): 201.266
• InChI Key: UIJXHKXIOCDSEB-MRVPVSSYSA-N
• PubChem CID: 1514398
• SMILES: CC(C)(C)OC(=O)N1CCCC(C1)O

• Molecular Formula: C10H19NO3
• MDL Number: MFCD04115306
• Synonym: r-1-boc-3-hydroxypiperidine, r-tert-butyl 3-hydroxypiperidine-1-carboxylate, tert-butyl 3r-3-hydroxypiperidine-1-carboxylate, r-1-n-boc-3-hydroxypiperidine, r-n-boc-3-hydroxypiperidine, r-1-boc-3-hydroxylpiperidine, 3r-1-tert-butoxycarbonyl-3-hydroxypiperidine, 1-piperidinecarboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester, 3r, r-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester, r-3-hydroxy-1-tert-butoxycarbonyl piperidine
• IUPAC Name: tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate

Specifications

• CAS: 143900-43-0
• Flash Point: 104°C (219°F)
• MDL Number: MFCD04115306
• InChI Key: UIJXHKXIOCDSEB-MRVPVSSYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCCC(C1)O
• Molecular Weight (g/mol): 201.266
• Formula Weight: 201.27
• Chemical Name or Material: (R)-1-Boc-3-hydroxypiperidine

• Melting Point: 46°C to 50°C
• Molecular Formula: C10H19NO3
• Synonym: r-1-boc-3-hydroxypiperidine, r-tert-butyl 3-hydroxypiperidine-1-carboxylate, tert-butyl 3r-3-hydroxypiperidine-1-carboxylate, r-1-n-boc-3-hydroxypiperidine, r-n-boc-3-hydroxypiperidine, r-1-boc-3-hydroxylpiperidine, 3r-1-tert-butoxycarbonyl-3-hydroxypiperidine, 1-piperidinecarboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester, 3r, r-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester, r-3-hydroxy-1-tert-butoxycarbonyl piperidine
• Optical Rotation: −23° (c=5 in Methanol)
• IUPAC Name: tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate
• PubChem CID: 1514398
• Percent Purity: 97%

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c

H301-H315-H318-H335

missing translation for 'dotInformation' : Hazard Class: 6.1; Packaging Group: III

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

RUO – Research Use Only