Quinine hemisulfate monohydrate, 98+%

Product Code.	Quantity	unitSize
11468896	250 g	250g
11448896	10 g	10g
11458896	50 g	50g

Product Code. 11468896 Supplier Thermo Scientific Alfa Aesar Supplier No. A17036.30

Beschreibung

CAS: 6119-70-6 | C40H54N4O10S | 782.95 g/mol

Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Solubility
Soluble in a mixture of chloroform and absolute alcohol (2:1).

Notes
Light sensitive. Incompatible with strong oxidizing agents, alkalis, ammonia, strong bases and iodine.

Spezifikation

Chemische Identifikatoren

• CAS: 6119-70-6
• Molecular Formula: C40H54N4O10S
• Molecular Weight (g/mol): 782.95
• MDL Number: MFCD00150790
• InChI Key: ZHNFLHYOFXQIOW-OIGVVMIYNA-N
• Synonym: Quinine sulfate (2:1) (salt) dihydrate; Quinine sulfate dihydrate
• PubChem CID: 134129495
• IUPAC Name: (R)-[(2R,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;tetrahydrate
• SMILES: O.O.OS(O)(=O)=O.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C

• Melting Point: 217°C to 218°C (decomposition)
• Odor: Odorless
• Quantity: 250 g
• Beilstein: 6113937
• Sensitivity: Light sensitive
• Merck Index: 14,8061
• Solubility Information: Soluble in a mixture of chloroform and absolute alcohol (2:1).
• Optical Rotation: −241° (c=2 in 0.1M HCl)
• Formula Weight: 391.47 (373.46 Anhydrous)
• Percent Purity: 99%
• Chemical Name or Material: Quinine hemisulfate monohydrate

Sicherheit und Handhabung

Sicherheitsdatenblatt (SDS)

RUO – Research Use Only