Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine

Code produit	Quantity	unitSize
11478683	10 g	10g
11488683	50 g	50g
11498683	250 g	250g

Code produit 11478683 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur A10459.09

Description

CAS: 130-95-0 | C20H24N2O2 | 324.42 g/mol

Quinine is used in photochemistry as a common fluorescence standard and as a resolving agent for chiral acids. It is also useful for treating falciparum malaria, lupus, arthritis and vivax malaria. It acts as a flavor component in tonic water and bitter lemon. It is utilized as the chiral moiety for the ligands used in sharpless asymmetric dihydroxylation. Furthermore, it catalyzes the kinetic resolution of furanones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinine is used in photochemistry as a common fluorescence standard and as a resolving agent for chiral acids. It is also useful for treating falciparum malaria, lupus, arthritis and vivax malaria. It acts as a flavor component in tonic water and bitter lemon. It is utilized as the chiral moiety for the ligands used in sharpless asymmetric dihydroxylation. Furthermore, it catalyzes the kinetic resolution of furanones.

Solubility
Soluble in alcohol, chloroform and diethyl ether. Slightly soluble in water and glycerol.

Notes
Incompatible with strong oxidizing agents.

Spécification

Identifiants chimiques

• CAS: 130-95-0
• Molecular Formula: C20H24N2O2
• Molecular Weight (g/mol): 324.42
• MDL Number: MFCD00198096
• InChI Key: LOUPRKONTZGTKE-ZCXAXGJJNA-N
• Synonym: 1r-6-methoxyquinolin-4-yl 1s,4s,5r-5-vinylquinuclidin-2-yl methanol, quinine anhydrous, +-2,3-o-isopropylidene-l-threitol
• PubChem CID: 129316724
• SMILES: [H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C

• Melting Point: ∼177°C (decomposition)
• Quantity: 10 g
• Beilstein: 91867
• Sensitivity: Light Sensitive
• Merck Index: 14,8061
• Solubility Information: Soluble in alcohol,chloroform and diethyl ether. Slightly soluble in water and glycerol.
• Optical Rotation: −166° (c=1 in ethanol)
• IUPAC Name: (R)-[(2S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol
• Formula Weight: 324.42
• Percent Purity: 99%
• Assay: (total base)
• Chemical Name or Material: Quinine, Anhydrous, may cont. up to 5% dihydroquinine

Sécurité et traitement

Identifiant produit

• Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine

Mention d'avertissement

• Warning

Catégorie de danger

• Acute toxicity Category 4
• Skin sensitiser Category 1

Mention de danger

• H302-Harmful if swallowed.
• H317-May cause an allergic skin reaction.

Conseils de prudence

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P333+P313-If skin irritation or rash occurs: Get medical advice/attention.

Informations supplémentaires

• MIXTURE LIST-Contain: Quinine

FDS

RUO – Research Use Only