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Quetiapine, MedChemExpress

Product Code. 16476486
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Product Code. 16476486 Supplier Medchem Express Supplier No. HY14544

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Description

MedChemExpress Quetiapine (ICI204636) is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine has moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects.

Quetiapine (ICI204636) is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine has moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects.

Specifications

Chemical Name or Material Quetiapine
CAS 111974-69-7
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C21H25N3O2S
Quantity 100 mg
Synonym ICI204636
Solubility Information Ethanol : 100 mg/mL (260.75 mM; Need ultrasonic) ∣DMSO : 100 mg/mL (260.75 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.26 mM; ultrasonic and warming and heat to 50°C)
SMILES OCCOCCN(CC1)CCN1C2=NC3=CC=CC=C3SC4=C2C=CC=C4
Molecular Weight (g/mol) 383.51
Formula Weight 383.51
Percent Purity 99.96%
Grade Research
Physical Form Oil
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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