Invitrogen™ QDPR Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110250

Product Code. 17108183

Description

Immunogen sequence: MAAAAAAGEA RRVLVYGGRG ALGSRCVQAF RARNWWVASV DVVENEEASA SIIVKMTDSF TEQADQVTAE VGKLLGEEKV DAILCVAGGW AGGNAKSKSL FKNCDLMWKQ SIWTSTISSH LATKHLKEGG LLTLAGAKAA LDGTPGMIGY GMAKGAVHQL CQSLAGKNSG MPPGAAAIAV LPVTLDTPMN RKSMPEADFS SWTPLEFLVE TFHDWITGKN RPSSGSLIQV VTTEGRTELT PAYF.

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Specifications

• Antigen: QDPR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: QDPR
• Gene Alias: 2610008L04Rik; 6,7-dihydropteridine reductase; D5Ertd371e; Dhpr; dihydropteridine reductase; HDHPR; HPR; PKU2; QDPR; Quinoid dihydropteridine reductase; SDR33C1; Short chain dehydrogenase/reductase family 33C member 1; short chain dehydrogenase/reductase family 33C, member 1; testis secretory sperm-binding protein Li 236P
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110391, 5860, 64192
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.23 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09417, P11348, Q8BVI4
• Gene Symbols: QDPR
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human QDPR (NP_000311.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG