PZ-2891, MedChemExpress

Artikelnummer.	Quantity	unitSize
16475876	100 mg	100mg
16457907	5 mg	5mg
16421407	50 mg	50mg
16405188	10 mg	10mg

Artikelnummer. 16475876 Lieferant Medchem Express Lieferanten-Nr. HY124634

Beschreibung

MedChemExpress PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively.

PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively.

Spezifikation

• Chemical Name or Material: PZ-2891
• CAS: 2170608-82-7
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₂₀H₂₃N₅O
• Quantity: 100 mg
• Solubility Information: DMSO : 75 mg/mL (214.64 mM; Need ultrasonic)
• SMILES: N#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1
• Molecular Weight (g/mol): 349.43
• Formula Weight: 349.43
• Percent Purity: 98.4%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Neuroscience-Neuromodulation

Research purposes only