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  7. Pyridine-2,3-dicarboxylic acid, 99%

Pyridine-2,3-dicarboxylic acid, 99%

Product Code. 11440253
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Product Code. 11440253 Supplier Thermo Scientific Alfa Aesar Supplier No. A11414.14
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Description

CAS: 89-00-9 | C7H5NO4 | 167.12 g/mol

Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an excitotoxic metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an “excitotoxic” metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.

Solubility
Soluble in water (partly), alkalies, dilute aqueous base, DMSO, and alcohol (slightly).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 89-00-9
Molecular Formula C7H5NO4
Molecular Weight (g/mol) 167.12
MDL Number MFCD00006295
InChI Key GJAWHXHKYYXBSV-UHFFFAOYSA-N
Synonym quinolinic acid, 2,3-pyridinedicarboxylic acid, quinolinate, pyridine-2,3-dicarboxylate, unii-f6f0hk1urn, 2,3-pyridinedicarboxylicacid, pyridine-2,3-carboxylate, f6f0hk1urn, pyridin-2,3-dicarbonsaeure, 2,3-pyridinedicarboxylate
PubChem CID 1066
ChEBI CHEBI:16675
IUPAC Name pyridine-2,3-dicarboxylic acid
SMILES C1=CC(=C(N=C1)C(=O)O)C(=O)O

Specifications

Melting Point ∼188°C (decomposition)
Quantity 25 g
Beilstein 137110
Merck Index 14,8073
Solubility Information Soluble in water (partly),alkalies,dilute aqueous base,DMSO,and alcohol (slightly).
Formula Weight 167.12
Percent Purity 99%
Chemical Name or Material Pyridine-2,3-dicarboxylic acid

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