Invitrogen™ PYDC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA570122

Product Code. 15828533

Description

This target displays homology in the following species: Cow: 83%; Dog: 83%; Goat: 83%; Guinea Pig: 85%; Horse: 83%; Human: 100%; Yeast: 77%.

ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

Specifications

• Antigen: PYDC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PYDC1
• Gene Alias: ASC2; ASCI; cellular POP1; cPOP1; PAAD-only protein 1; POP1; PYC1; PYD (pyrin domain) containing 1; PYDC1; pyrin domain containing 1; pyrin domain-containing protein 1; Pyrin-only protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 260434
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8WXC3
• Gene Symbols: PYDC1
• Immunogen: synthetic peptide directed towards the N-terminal region of human PYDC1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG