Invitrogen™ PXDN Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5144080

Product Code. 17961851

Description

Positive Control - WB: human Hela whole cell, human U251 whole cell, rat heart tissue, mouse heart tissue. IHC: human pancrease cancer tissue, human renal cancer tissue.

Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.

Specifications

• Antigen: PXDN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PXDN
• Gene Alias: 2310075M15Rik; C85409; COPOA; D2S448; D2S448E; E330004E07; Kiaa0230; Melanoma-associated antigen MG50; MG50; mKIAA0230; p53-responsive gene 2 protein; PE responsive protein c64; Perc64; peroxidasin; peroxidasin homolog; peroxidasin homolog (Drosophila); PRG2; PXDN; PXN; Vascular peroxidase 1; VPO; VPO1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 554172, 69675, 7837
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q3UQ28, Q92626
• Gene Symbols: PXDN
• Immunogen: Human PXDN between 900-1064.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG