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  7. PX 12, Tocris Bioscience™

PX 12, Tocris Bioscience™

Catalog Number p-4784377
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Quantity:
10 mg
50 mg
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141400-58-0
C7H12N2S2
188.31
MFCD18086851
BPBPYQWMFCTCNG-UHFFFAOYNA-N
2-sec-butyldisulfanyl-1h-imidazole, 2-1-methylpropyl dithio-1h-imidazole, 2-butan-2-yldisulfanyl-1h-imidazole, 1h-imidazole,2-1-methylpropyl dithio, 1h-imidazole, 2-1-methylpropyl dithio, iv 2 compound, iv-2 compound, 1-methylpropyl-2-imidazolyl disulfide
219104
2-(butan-2-yldisulfanyl)-1H-imidazole
CCC(C)SSC1=NC=CN1
This item is not returnable. View return policy
141400-58-0
C7H12N2S2
188.31
MFCD18086851
BPBPYQWMFCTCNG-UHFFFAOYNA-N
2-sec-butyldisulfanyl-1h-imidazole, 2-1-methylpropyl dithio-1h-imidazole, 2-butan-2-yldisulfanyl-1h-imidazole, 1h-imidazole,2-1-methylpropyl dithio, 1h-imidazole, 2-1-methylpropyl dithio, iv 2 compound, iv-2 compound, 1-methylpropyl-2-imidazolyl disulfide
219104
2-(butan-2-yldisulfanyl)-1H-imidazole
CCC(C)SSC1=NC=CN1

Description

Thioredoxin-1 inhibitor

Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo.
Quantity 10 mg
Formula Weight 188.31
Percent Purity >99%
Chemical Name or Material PX 12
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