Invitrogen™ PUS10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550738

Product Code. 15664665

Description

The antibody detects endogenous levels of total PUS10 protein.

Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.

Specifications

• Antigen: PUS10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pus10
• Gene Alias: 2810013G11Rik; 4933435A13Rik; AU014648; C77560; CCDC139; coiled-coil domain containing 139; coiled-coil domain-containing protein 139; DOBI; pseudouridine synthase 10; pseudouridylate synthase 10; psi55 synthase; Pus10; Putative tRNA pseudouridine synthase Pus10; RGD1306402; tRNA pseudouridine 55 synthase; tRNA pseudouridylate synthase; tRNA-uridine isomerase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 150962, 74467
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.8 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q3MIT2, Q9D3U0
• Gene Symbols: Pus10
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human pseudouridylate synthase 10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG